Pure Source.
Ultimate Safety.
Featuring the world-leading Y-Shape Polyethylene Glycol (PEG) patented structure.
Purer raw materials, clearer metabolism. Less burden, more peace of mind for growth.
Innovative Technology
Pegpesen represents a paradigm shift in biopharmaceuticals, utilizing proprietary pegylation to achieve stable, long-acting delivery.
Y-Shape PEG Structure
Our exclusive 40kD Y-shaped branched polyethylene glycol (PEG) structure significantly increases the molecular weight. This effectively reduces renal clearance and protects the molecule from enzymatic degradation, extending the half-life to enable once-weekly dosing.
Yeast Expression System
Unlike traditional E. coli expression systems, our unique Yeast Expression System produces proteins that are structurally closer to natural human growth hormone. This results in lower immunogenicity and reduced risk of allergic reactions for long-term safety.
The Safety Trinity
A holistic approach to safety: Source, Process, and Experience.
Source Purity
- Yeast Expression System (Low Immunogenicity)
- Pharma-Grade PEG Material
Structural Safety
- Patented Y-Shape Structure
- Lowest Starting Dose (Reduced Exposure)
Clinical Superiority
Key Scientific Publications
A Novel Y-Shaped Pegylated Recombinant Human Growth Hormone for Children with GHD
This multicenter, randomized, controlled phase 3 study confirmed that weekly Pegpesen is non-inferior to daily rhGH (Norditropin), demonstrating comparable safety and efficacy profiles with significantly fewer injections.
Read Article →Optimization of Dosing Regimens for Long-Acting Growth Hormone Pegpesen
A population PK/PD modeling approach to optimize dosing strategies, ensuring stable therapeutic levels and minimizing fluctuations while maintaining safety standards for pediatric patients.
Read Abstract →
Smart Injection
Zero Anxiety
Our IoT Smart Pen features a Hidden Needle design and digital tracking, transforming the treatment experience for children. By eliminating preservatives and harsh excipients, we minimize pain and maximize compliance.