Inpegsomatropin · Clinical referenceLiterature reviewed 28 September 2026

Once-weekly growth hormone · Pediatric GHD

The science.
The evidence.
The weekly rhythm.

Pegpesen® (inpegsomatropin) is a long-acting growth hormone developed by Amoytop. Explore the product, understand the clinical program, and keep up with the research.

Source-linked information for healthcare professionals.

InpegsomatropinProduct profile / 01
Pegpesen inpegsomatropin injection packaging and injection device, official Amoytop product image
Pegpesen®怡培生长激素注射液 · 益佩生®
Amoytop source ↗
Once weeklySubcutaneous administration
3+ yearsChina label: pediatric GHD
391Children in the Phase III trial
52 weeksPivotal comparison with daily GH

Research watch / September 2026

A closer look at the latest.

View the research library ↗
NEW TO THE LIBRARYAugust 2026 · Endocrine Practice

Where does Pegpesen sit in the long-acting GH evidence?

A network meta-analysis of five studies includes Pegpesen, Jintrolong, and somapacitan. Read the comparative findings with the limits of indirect evidence in view.

Read the study summary ↗
CONFERENCE ABSTRACTENDO 2026

Exploring non-GHD short stature

A 52-week Phase II basket trial in 78 children reports findings across ISS, SGA, and Turner syndrome.

Read the preliminary findings ↗
MODEL-BASED RESEARCHMarch 2026 issue

A different lens on weekly dosing

The population PK/PD study explores dose titration and weight bands through simulation.

Explore the modeling paper ↗

The pivotal study

A weekly regimen.
A 52-week comparison.

The randomized Phase III trial compared weekly Pegpesen with daily somatropin in treatment-naïve children with GHD. The study met its prespecified non-inferiority criterion for growth velocity.

Study design, outcomes & safety ↗